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Centre for Bioinformatics
Division of Molecular Biosciences
Faculty of Natural Sciences
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Seminar Series

We hold regular seminars, generally on Mondays, at 4.30pm. The seminars are followed by a drinks reception in the Sherfield Building, Senior Common Room from 5:30-6:30pm. All are welcome to our seminars. To join the mailing list or for further information please contact:

For Maps & Travel information please go to this link. Please note that:

  • Biochemisty Building is No 4 on Campus Map
  • Sir Alexander Fleming Building (SAF) is No 5 on Campus Map
  • Flowers Building is No 30 on Campus Map

    • Monday 9th November 4.45pm
    Professor Mark Sansom
    Deptartment of Biochemistry, University of Oxford
    Multiscale Simulations of Membrane Proteins
    Membrane proteins account for nearly a quarter of all genes. However, much remains to be understood concerning their structure and function. Most membrane proteins have transmembrane domains made up of bundles of hydrophobic α-helices. The lateral association of TM helices within a lipid bilayer environment is a key stage in the folding of membrane proteins. It may also play a role in signalling across cell membranes. Coarse-grained molecular dynamics simulations may be used to probe the interactions of membrane proteins with bilayers and their component lipids on an extended (~1 µs) timescale. Conversion to atomistic resolution allows protein/lipid and protein/protein interactions to be examined in greater detail. This multiscale approach will be examined via examples from ongoing studies of a range of membrane protein systems including: (i) transmembrane helix dimerization within cell membranes; and (ii) interactions of interactions of PIP2 with the inward rectifier potassium channels
    Read Lecture Theatre, Sherfield building

    Friday 20th November 4pm
    Dr Chze Ling Wee
    Dept of Biochemistry, University of Oxford
    Membrane Insertion of a Voltage Sensor Helix via Multi-Scale Molecular Dynamics Simulations
    http://www.lincoln.ox.ac.uk/content/view/856/40/
    7th floor common room, Biochemistry building

    Monday 30th November 4.30pm
    Professor Dek Woolfson
    University of Bristol.
    Title TBA
    http://www.bris.ac.uk/biochemistry/research/dnw.html
    G34 Sir Alexander Fleming (SAF) building

     

    Statistical Genetics Seminars

    The seminars will be held approximately monthly, and will usually be in the

      Roger Bannister Lecture Theatre
      1st Floor, Medical School Building
      Norfolk Place, Paddington
    The main entrance to the building is now controlled by swipe-card barriers. Some but not all IC swipe cards will work; if not you can request access if you are a frequent visitor. The entrance is staffed at all times and non-IC people should address themselves to the security desk, state their purpose, and not be carrying any weapons of mass destruction or similar. For additions/removals to the list please contact Madeline Kirk m.kirk@imperial.ac.uk. For suggestions of speakers etc please e-mail Professor David Balding d.balding@imperial.ac.uk.

     

    Last Modified 29 October 2007