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2017 Sir Ernst Chain Lecture by Professor Ada Yonath

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The Department of Life Science cordially invites you to join us for

The 2017 Sir Ernst Chain Lecture

"Key issues in medicine:
resistance to antibiotics and environmental concerns"

Professor Ada Yonath
Weizmann Institute, Israel
Recipient of the 2009 Nobel Prize for Chemistry

Thursday 23 March at 5pm, followed by a drinks reception 6:15-7pm
G16 - 1st Floor Sir Alexander Fleming Building
Imperial College London
South Kensington Campus SW7 2AZ

Professor Ada Yonath is a crystallographer best known for her pioneering work on the structure of the ribosome. In 2009, she received the Nobel Prize in Chemistry along with Venkatraman Ramakrishnan and Thomas A. Steitz for her studies on the structure and function of the ribosome, becoming the first Israeli woman to win the Nobel Prize out of ten Israeli Nobel laureates, the first woman from the Middle East to win a Nobel prize in the sciences, and the first woman in 45 years to win the Nobel Prize for Chemistry.

In her lecture Professor Yonath will focus on the challenge of resistance to antibiotics and the spread of antibiotics' metabolites in the environment which are severe problems in contemporary medicine. Ribosomes, the cellular organelles for the translation of the genetic code into proteins are a major target for antibiotics.

Structures of complexes of eubacterial-ribosomes with antibiotics paralyzing them illuminated common pathways in the modes of antibiotics inhibitions, synergism, differentiation and resistance. Furthermore, recent structures of ribosome from a multi-resistant pathogenic bacterium identified features that can account for species-specific diversity in infectious-diseases susceptibility. Careful analysis and comparisons to ribosomes from benign bacteria identified unique structural features that may lead to the design of species-specific environmental-friendly degradable antibiotics, thus protecting the environment alongside preserving the microbiome.

Attendance is free but REGISTRATION IS REQUIRED (form below) as we expect to be over subscribed.

For administrative enquiries please contact

Ms Sandrine Nurboja s.nurboja@imperial.ac.uk

For academic enquiries please contact

Professor Michael JE Sternberg m.sternberg@imperial.ac.uk

Finding us

- South Kensington Campus map (SAF is bulding no. 33 on map) (PDF file)
- Schematic map of local area (PDF file)
- Travel information (train, underground, bus, car & air)(Imperial web site)
- London Underground map (PDF file)
Please note that there is no car parking on the South Kensington campus. There is on street meter parking, but this is limited.

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